Drug discovery and development

New research from the ICR is showing us how additional measurements taken by MRI could speed up the development of new drugs that could make chemotherapies more effective

FOCUS4 was a large-scale trial investigating new treatments in people with advanced or metastatic colorectal cancer. Running it may not have been without its challenges, but the learnings it provided us with are invaluable if we’re to run trials like it again. 

Researchers in Southampton have found a way to improve the effectiveness of immunotherapy in cancers that are resistant by repurposing existing drugs

In an unusual turn of events, the results of a clinical trial for mitoxantrone turned out to be so effective that the randomisation of the trial was halted early. 

You may not know that as well as funding cancer research, we also work with industry and academia to develop promising ideas and turn them into real benefit for patients. Find out about Cancer Research Horizons.

Forty years ago, hints of a new component of the immune system caused a stir. Here, we chart the story of gamma delta T cells from discovery to clinical trials…

“Our motivation for studying it is because there haven’t been any new effective treatments for decades.” Overall, survival for children’s…

To mark 20 years since the merger of the Cancer Research Campaign and the Imperial Cancer Research Fund, we’ve delved into the research of the charities’ that led to many of the drugs in use today.

Pioneering therapeutics targeting the damage repair mechanism of DNA polymerase theta in a range of cancers have entered human trials – we tell the story from discovery to translation.

From groundbreaking rare cancer research to ending up on Forbes 30 under 30, we chat to Sigourney Bell about her work in the lab and her global organisation, Black in Cancer.