Drug resistance

Researchers have found a drug that targets the tumour microenvironment that could improve treatment for certain cancers. But it might not be the kind of drug you expect. 

Cancer Research UK-funded scientists are using innovative techniques to understand how resistance to a targeted cancer drug is unfolding.

New research shows a type of aggressive blood cancer could be made more sensitive to chemotherapy using an antibiotic currently available to treat diarrhoea.

Chemotherapy can cause some of the healthy cells surrounding a tumour to make proteins that encourage hardy tumour cells to start growing again

A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment, according to new research published in Nature Medicine.

Cancer Research UK scientists have shown how the level of genetic chaos in tumours could help predict patients’ response to chemotherapy.

Immune cells may be responsible for drug resistance in melanoma patients, according to research published in Cancer Discovery.

Scientists have discovered how two genes cause bowel cancer cells to become resistant to treatments used against the disease.

Rapid resistance to vemurafenib – a treatment for a type of skin cancer – could be prevented by blocking a druggable family of proteins

Cancer Research UK scientists have discovered that the commonest type of ovarian cancer evolves at a startling rate, which may allow cancer cells to ‘dodge’ the current standard treatment, reveals research in The Journal of Pathology today.