BRCA gene mutations

• Health & Medicine

Olaparib approved for 800 prostate and breast cancer patients in England

Olaparib, a targeted cancer drug discovered and developed with our funding, has been approved for hundreds of patients with certain breast and prostate cancers in England.  Olaparib, a targeted cancer drug discovered and developed with our funding, has been approved for hundreds of patients with certain breast and prostate cancers in England. 

11 April 2023

• Personal Stories

How serendipity sent this oncologist in search of a cure for cancer

Dr Hugo De La Peña, the face of our latest TV advert, explains how a second chance at life led to a career dedicated to curing cancer.   Dr Hugo De La Peña, the face of our latest TV advert, explains how a second chance at life led to a career dedicated to curing cancer.  

12 August 2022

• Science & Technology
• Health & Medicine

Prising open the trap: Getting to grips with targeted cancer drug resistance

Cancer Research UK-funded scientists are using innovative techniques to understand how resistance to a targeted cancer drug is unfolding. Cancer Research UK-funded scientists are using innovative techniques to understand how resistance to a targeted cancer drug is unfolding.

10 January 2022

• Science & Technology

Professor Stephen West awarded Cancer Research UK’s lifetime achievement prize

Professor Stephen West of the Francis Crick Institute has been awarded the Cancer Research UK lifetime achievement award for his pioneering work in DNA repair. Professor Stephen West of the Francis Crick Institute has been awarded the Cancer Research UK lifetime achievement award for his pioneering work in DNA repair.

3 October 2018

• Science & Technology
• Health & Medicine

NICE publishes new guidance for women at high risk of breast cancer

Almost half a million healthy women at high risk of breast cancer can now be offered drugs that can cut their chances of developing the disease. Almost half a million healthy women at high risk of breast cancer can now be offered drugs that can cut their chances of developing the disease.

25 June 2013

• Health & Medicine

Hundreds more breast cancer patients should be tested for BRCA1 gene

Leading breast cancer experts are calling for women under 50 diagnosed with triple-negative breast cancer to be offered testing for faults in the BRCA1 gene. Leading breast cancer experts are calling for women under 50 diagnosed with triple-negative breast cancer to be offered testing for faults in the BRCA1 gene.

15 February 2012

Scientists discover first DNA region to alter breast cancer risk in women with BRCA1 faults

Cancer Research UK scientists have identified a DNA region which can increase or decrease the high breast cancer risk associated with the BRCA1 gene. Cancer Research UK scientists have identified a DNA region which can increase or decrease the high breast cancer risk associated with the BRCA1 gene.

19 September 2010

• Science & Technology

Gene study backs promise of breast cancer drugs to treat hereditary prostate cancer

How prostate cancer develops in men who have an altered 'breast cancer gene' is the same route by which breast cancer develops in women with the same mutation How prostate cancer develops in men who have an altered 'breast cancer gene' is the same route by which breast cancer develops in women with the same mutation

24 June 2010

• Health & Medicine

Cauliflower and broccoli boost cancer protection

Naturally occurring chemicals found in vegetables like broccoli, cauliflower and cabbage can enhance DNA repair in cells, which may stop them becoming cancerous Naturally occurring chemicals found in vegetables like broccoli, cauliflower and cabbage can enhance DNA repair in cells, which may stop them becoming cancerous

7 February 2006