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BRCA gene mutations

Showing 12 out of 16 results
Microscopic cross section of breast tissue stained for various cell markers against a black background.

Our researchers are looking for the earliest signs of breast cancer linked to BRCA mutations to find ways to prevent the disease altogether. Our researchers are looking for the earliest signs of breast cancer linked to BRCA mutations to find ways to prevent the disease altogether.

by Sydney Ghazarian | In depth | 10 September 2026

10 September 2026

A breast cancer cell seen through an electron microscope.

Our Partner trial has found a new treatment combination for women with inherited breast cancers, with all 39 patients who received it surviving the critical three years after surgery Our Partner trial has found a new treatment combination for women with inherited breast cancers, with all 39 patients who received it surviving the critical three years after surgery

by Amal Iman, Tim Gunn | News | 13 May 2025

13 May 2025

That Cancer Conversation in a white speech bubble with a dark blue background
  • Science & Technology
  • Health & Medicine

That Cancer Conversation podcast - Can I inherit cancer?

Welcome to another episode of Cancer Research UK's podcast, That Cancer Conversation. It's been 30 years since the discovery of BRCA genes, and to celebrate Sophie speaks to Professor Mike Stratton, who led the discovery of BRCA2, and a family who has the BRCA2 mutation. Welcome to another episode of Cancer Research UK's podcast, That Cancer Conversation. It's been 30 years since the discovery of BRCA genes, and to celebrate Sophie speaks to Professor Mike Stratton, who led the discovery of BRCA2, and a family who has the BRCA2 mutation.

by Cancer Research UK | Podcast | 30 October 2024

30 October 2024

This entry is part 22 of 38 in the series That Cancer Conversation
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Lina speaks to Dr Hugo De La Pena who is looking at cancer scans on a computer screen

Lina tells the story of how a newly available targeted drug helped slow down the growth of faulty BRCA-driven cancer in her body, giving her more time to spend with her loved ones. Lina tells the story of how a newly available targeted drug helped slow down the growth of faulty BRCA-driven cancer in her body, giving her more time to spend with her loved ones.

by Elisa Mitchell, Amy Warnock | Personal stories | 28 October 2024

28 October 2024

Microscopic image of core biopsy for infiltrating (invasive) ductal carcinoma, detected by screening mammogram

Our researchers have published a paper showing that their alternative BRCA testing pathway, BRCA-DIRECT, could be a more convenient way to test for faulty BRCA genes in people with breast cancer Our researchers have published a paper showing that their alternative BRCA testing pathway, BRCA-DIRECT, could be a more convenient way to test for faulty BRCA genes in people with breast cancer

by Fiona Scott | News | 1 October 2024

1 October 2024

Radiographer looking at a mammogram image

Since the discovery of the BRCA genes 30 years ago, we’ve made huge leaps forward in understanding faulty BRCA-driven cancers – leaps that are saving and improving lives right now​. Since the discovery of the BRCA genes 30 years ago, we’ve made huge leaps forward in understanding faulty BRCA-driven cancers – leaps that are saving and improving lives right now​.

by Amy Warnock | In depth | 1 October 2024

1 October 2024

Breast cancer cells

Olaparib, a targeted cancer drug discovered and developed with our funding, has been approved for hundreds of patients with certain breast and prostate cancers in England.  Olaparib, a targeted cancer drug discovered and developed with our funding, has been approved for hundreds of patients with certain breast and prostate cancers in England. 

by Tim Gunn | News | 11 April 2023

11 April 2023

Dr Hugo De La Peña in front of University Hospital Southampton

Dr Hugo De La Peña, the face of our latest TV advert, explains how a second chance at life led to a career dedicated to curing cancer.   Dr Hugo De La Peña, the face of our latest TV advert, explains how a second chance at life led to a career dedicated to curing cancer.  

by Elisa Mitchell | Personal stories | 12 August 2022

12 August 2022

Breast cancer screening

Cancer Research UK-funded scientists are using innovative techniques to understand how resistance to a targeted cancer drug is unfolding. Cancer Research UK-funded scientists are using innovative techniques to understand how resistance to a targeted cancer drug is unfolding.

by Lilly Matson | Analysis | 10 January 2022

10 January 2022