Immune system

• Science & Technology

Fighting fire with fire: could Salmonella treat bowel cancer?

Our researchers are modifying Salmonella bacteria into a treatment that can work with the immune system to attack bowel cancer from two sides at once. Our researchers are modifying Salmonella bacteria into a treatment that can work with the immune system to attack bowel cancer from two sides at once.

23 January 2025

• Health & Medicine
• Science & Technology

Thousands of NHS patients to access trials of personalised cancer 'vaccines'

Thousands of cancer patients in England are set to gain fast-tracked access to trials of personalised cancer vaccines following the launch of a world-leading NHS trial ‘matchmaking' service Thousands of cancer patients in England are set to gain fast-tracked access to trials of personalised cancer vaccines following the launch of a world-leading NHS trial ‘matchmaking' service

31 May 2024

• Science & Technology

The secret in cancer cells that can make immunotherapy more effective

Our researchers have found mutations that make cancers much more likely to respond to immunotherapy. It's a chance to make breakthrough treatments work for many more people. Our researchers have found mutations that make cancers much more likely to respond to immunotherapy. It's a chance to make breakthrough treatments work for many more people.

31 January 2024

• For Researchers

MOv18 - opening a new front for immunotherapy

Follow Sophia Karagiannis and James Spicer on an immunological adventure as they develop a ground-breaking new class of drug... Follow Sophia Karagiannis and James Spicer on an immunological adventure as they develop a ground-breaking new class of drug...

12 December 2023

• Science & Technology

Why does cancer seem to be so rare in bats?

Bats rarely get cancer. They also resist viruses that kill humans, and some don't even seem to age. Scientists think that it might have something to do with their ability to fly – and that we can copy some of their tricks. Bats rarely get cancer. They also resist viruses that kill humans, and some don't even seem to age. Scientists think that it might have something to do with their ability to fly – and that we can copy some of their tricks.

31 October 2023

• For Researchers

The power of partnership – the unique alliance taking on brain cancer

The Antibody Alliance Laboratory – a collaboration between Cancer Research UK and AstraZeneca – combines academic rigour with agile bioengineering to push forward antibody discovery projects... The Antibody Alliance Laboratory – a collaboration between Cancer Research UK and AstraZeneca – combines academic rigour with agile bioengineering to push forward antibody discovery projects...

15 December 2022

• Science & Technology
• Health & Medicine

Repurposing radiotherapy drugs could give immunotherapy a boost

Researchers in Southampton have found a way to improve the effectiveness of immunotherapy in cancers that are resistant by repurposing existing drugs Researchers in Southampton have found a way to improve the effectiveness of immunotherapy in cancers that are resistant by repurposing existing drugs

11 November 2022

• Health & Medicine

Immune cell count could determine whether chemotherapy is required in oropharyngeal cancer, new study finds 

A new study has found that the level of a person's immune cells may provide an indication of whether they would benefit from chemotherapy in oropharyngeal cancer. A new study has found that the level of a person's immune cells may provide an indication of whether they would benefit from chemotherapy in oropharyngeal cancer.

2 May 2022

• For Researchers

A new approach to cancer immunotherapy

Forty years ago, hints of a new component of the immune system caused a stir. Here, we chart the story of gamma delta T cells from discovery to clinical trials... Forty years ago, hints of a new component of the immune system caused a stir. Here, we chart the story of gamma delta T cells from discovery to clinical trials...

18 March 2022

• Science & Technology

The long road to targeting the holy grail of the immune response

A team of our scientists at University College London have developed a potential new immunotherapy drug and caused another paradigm shift in our understanding of how cancer immunotherapy works. A team of our scientists at University College London have developed a potential new immunotherapy drug and caused another paradigm shift in our understanding of how cancer immunotherapy works.

9 November 2020

• Science & Technology

Moves and countermoves: How the immune system responds to lung cancer’s ‘tactics’

Scientists working on the TRACERx project have mapped how the immune systems responds to lung tumours over time Scientists working on the TRACERx project have mapped how the immune systems responds to lung tumours over time

4 June 2020