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Research and trials

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The DETERMINE trial team celebrating at the Bionow awards

Since launching in December 2021, the DETERMINE trial has hit many milestones on the way to providing much needed treatment options for people with rare cancers, including treating its 100th patient. On Rare Disease Day, we look back at some of those key achievements. Since launching in December 2021, the DETERMINE trial has hit many milestones on the way to providing much needed treatment options for people with rare cancers, including treating its 100th patient. On Rare Disease Day, we look back at some of those key achievements.

by Tim Bodicoat | In depth | 28 February 2025

28 February 2025

A green beam of light from a radiotherapy machine.

Modern radiotherapy is used to treat more than 140,000 people with cancer in the UK every year. We've brought it a long way since 1896. Here's the full story. Modern radiotherapy is used to treat more than 140,000 people with cancer in the UK every year. We've brought it a long way since 1896. Here's the full story.

by Tim Gunn | In depth | 17 February 2025

17 February 2025

Salmonella bacteria (rod-shaped organisms coloured blue) in a bowel cancer tumour (coloured beige). The bacteria looks like it is rushing into a hole in the tumour tissue.

Our researchers are modifying Salmonella bacteria into a treatment that can work with the immune system to attack bowel cancer from two sides at once. Our researchers are modifying Salmonella bacteria into a treatment that can work with the immune system to attack bowel cancer from two sides at once.

by Tim Gunn, Fiona MacLeod | News | 23 January 2025

23 January 2025

Data centre filled with rows of servers

Today, Cancer Research UK, the National Institute for Health and Care Research (NIHR) and the Engineering and Physical Sciences Research Council (EPSRC) are announcing £10 million to create the Cancer Data-Driven Detection programme, which aims to use data to identify individual cancer risk. Today, Cancer Research UK, the National Institute for Health and Care Research (NIHR) and the Engineering and Physical Sciences Research Council (EPSRC) are announcing £10 million to create the Cancer Data-Driven Detection programme, which aims to use data to identify individual cancer risk.

by Amy Warnock, Graeme Sneddon | News | 22 January 2025

22 January 2025

Two Cancer Research UK researchers working at a lab bench.

We look back on how more than 10-years of mission-based funding has transformed the UK lung cancer research ecosystem and what our new mission focused government can learn from our approach. We look back on how more than 10-years of mission-based funding has transformed the UK lung cancer research ecosystem and what our new mission focused government can learn from our approach.

by Nick Jones | Analysis | 13 January 2025

13 January 2025

Dr Yin Cao and a colleague looking at data about cancer incidence.

Rising rates of early-onset bowel cancer are a “global phenomenon” and some of the steepest increases are happening in England, according to a major new paper we helped fund. Rising rates of early-onset bowel cancer are a “global phenomenon” and some of the steepest increases are happening in England, according to a major new paper we helped fund.

by Tim Gunn | News | 11 December 2024

11 December 2024

The capsule sponge shown in pill form and sponge form. Both are black and attached to a white thread.

Our BEST4 Screening trial will give 120,000 people with chronic heartburn a 'pill-on-a-thread' test to look for signs of Barrett's oesophagus, a rare condition that can lead to oesophageal cancer. The results will show whether the UK can use the test for a new oesophageal cancer screening programme. Our BEST4 Screening trial will give 120,000 people with chronic heartburn a 'pill-on-a-thread' test to look for signs of Barrett's oesophagus, a rare condition that can lead to oesophageal cancer. The results will show whether the UK can use the test for a new oesophageal cancer screening programme.

by Tim Gunn | Analysis | 28 November 2024

28 November 2024

Grapes

Scientists, funded by Cancer Research UK, are finding out if an ingredient commonly found in red grapes could hold the answer to help prevent bowel cancer. Scientists, funded by Cancer Research UK, are finding out if an ingredient commonly found in red grapes could hold the answer to help prevent bowel cancer.

by Sophie Wedekind | News | 11 November 2024

11 November 2024

A graphic showing analysis from a genomic test.
  • Science & Technology
  • Health & Medicine
  • Policy & Insight

The story of genomics - and our plan for its next chapter

Genomics is taking us from a ‘one size fits all’ approach to cancer care to one that's much more personalised. But that change is happening quickly, and the health system is struggling to keep up. Here's our plan for making sure that genomics benefits the whole of the UK. Genomics is taking us from a ‘one size fits all’ approach to cancer care to one that's much more personalised. But that change is happening quickly, and the health system is struggling to keep up. Here's our plan for making sure that genomics benefits the whole of the UK.

by Emily Eagles, Tim Gunn | In depth | 7 November 2024

7 November 2024