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Cancer genes

Showing 12 out of 303 results
Steph Phillips, Dr Miriam Dixon-Zegeye & Professor Sarah Blagden

We're funding the UK's first precision cancer prevention trial unit. It's testing a drug that could help protect people with Li Fraumeni Syndrome, a genetic condition that can lead to a more than 90% lifetime risk of cancer, against the disease. We're funding the UK's first precision cancer prevention trial unit. It's testing a drug that could help protect people with Li Fraumeni Syndrome, a genetic condition that can lead to a more than 90% lifetime risk of cancer, against the disease.

by Tim Gunn | In depth | 19 September 2023

19 September 2023

An African elephant walking along a dirt track

For World Elephant Day, we're taking a look at why elephants so rarely get cancer. Could the ways they protect themselves help people too? For World Elephant Day, we're taking a look at why elephants so rarely get cancer. Could the ways they protect themselves help people too?

by Tim Gunn | Analysis | 12 August 2023

12 August 2023

Links between retrotransposable elements and cancer have deep roots – George Kassiotis gets into their chequered past and how we might utilise these ancient viral infections   Links between retrotransposable elements and cancer have deep roots – George Kassiotis gets into their chequered past and how we might utilise these ancient viral infections  

by Cancer Research UK | In depth | 11 July 2023

11 July 2023

A cancer cell undergoing mitosis, or cloning itself and splitting in two.

Aggressive cancers use ecDNA to evolve quickly and resist treatment. This is how we found that out, and how we're going to stop it. Aggressive cancers use ecDNA to evolve quickly and resist treatment. This is how we found that out, and how we're going to stop it.

by Tim Gunn | In depth | 20 February 2023

20 February 2023

Pioneering therapeutics targeting the damage repair mechanism of DNA polymerase theta in a range of cancers have entered human trials - we tell the story from discovery to translation. Pioneering therapeutics targeting the damage repair mechanism of DNA polymerase theta in a range of cancers have entered human trials - we tell the story from discovery to translation.

by Cancer Research UK | In depth | 5 November 2021

5 November 2021

We speak to Professor Shankar Balasubramanian about his work on NGS, his incredible translational journey and the power of the pub… We speak to Professor Shankar Balasubramanian about his work on NGS, his incredible translational journey and the power of the pub…

by Phil Prime | Interview | 15 October 2021

15 October 2021

  • Health & Medicine
  • Science & Technology

Discovering the BRCA2 gene – 25 years on

25 years ago, a team of our scientists were celebrating. Their risky strategy had paid off. 25 years ago, a team of our scientists were celebrating. Their risky strategy had paid off.

by Katie Roberts | Analysis | 14 January 2021

14 January 2021

Samples in the lab

Research reveals how genetic variations in the regions of DNA that don't code for proteins, once dismissed as 'junk DNA', can affect a person's risk of cancer. Research reveals how genetic variations in the regions of DNA that don't code for proteins, once dismissed as 'junk DNA', can affect a person's risk of cancer.

by British Journal of Cancer | News | 6 December 2019

6 December 2019