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Cancer Grand Challenges

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A microscope image showing cells affected by Barrett's oesophagus, a precancer that can lead to oesophageal cancer.

For oesophageal cancer awareness month, we’ve rounded up four of our articles on the latest research into oesophageal cancer diagnosis, treatment and prevention.   For oesophageal cancer awareness month, we’ve rounded up four of our articles on the latest research into oesophageal cancer diagnosis, treatment and prevention.  

by Amy Warnock | Analysis | 9 February 2024

9 February 2024

Two researchers smiling as they work together in a lab

2023 has been a big year for Cancer Research UK, and there's been a lot to celebrate. So, to end the year, we want to highlight just a few of our most exciting research stories of 2023. 2023 has been a big year for Cancer Research UK, and there's been a lot to celebrate. So, to end the year, we want to highlight just a few of our most exciting research stories of 2023.

by Jacob Smith | In depth | 18 December 2023

18 December 2023

Cancer cells with extrachromosomal DNA (ecDNA)

Cancer Grand Challenges team eDyNAmiC has changed our understanding of how oesophageal cancer starts. In some cases, mutations scientists thought were a late effect of the disease could actually be driving it in the first place. The findings could give us a new way to intercept cancer before it becomes dangerous. Cancer Grand Challenges team eDyNAmiC has changed our understanding of how oesophageal cancer starts. In some cases, mutations scientists thought were a late effect of the disease could actually be driving it in the first place. The findings could give us a new way to intercept cancer before it becomes dangerous.

by Tim Gunn | In depth | 23 October 2023

23 October 2023

The flags of the UK and France flying side by side

Cancer Research UK and France’s Institut National Du Cancer (INCa) have announced a new scientific partnership to help fund world-class researchers to take on cancer’s toughest challenges Cancer Research UK and France’s Institut National Du Cancer (INCa) have announced a new scientific partnership to help fund world-class researchers to take on cancer’s toughest challenges

by Jacob Smith | News | 27 September 2023

27 September 2023

Her Majesty Queen Letizia of Spain, honorary president of the Spanish Association Against Cancer (AECC), visited Cancer Research UK today to commemorate the upcoming World Cancer Research Day. Her Majesty Queen Letizia of Spain, honorary president of the Spanish Association Against Cancer (AECC), visited Cancer Research UK today to commemorate the upcoming World Cancer Research Day.

by Jacob Smith | News | 21 September 2023

21 September 2023

Graphic announcing the Cancer Grand Challenges shortlist

The Cancer Grand Challenges shortlist includes 12 teams with the potential to make the progress against cancer that we urgently need. The Cancer Grand Challenges shortlist includes 12 teams with the potential to make the progress against cancer that we urgently need.

by Tim Gunn | News | 5 September 2023

5 September 2023

Cancer Grand Challenges Scientific Committee member Professor Karen Vousden presenting at the Cancer Grand Challenges summit in London, March 2023

We're nearly 10 years into the Cancer Grand Challenges story. Dr Iain Foulkes, our executive director of Research & Innovation, gives an inside view on it. We're nearly 10 years into the Cancer Grand Challenges story. Dr Iain Foulkes, our executive director of Research & Innovation, gives an inside view on it.

by Iain Foulkes | Opinion | 4 September 2023

4 September 2023

Doctor reviewing a mammogram

New research may have found a way we can predict which cases of DCIS could develop into invasive breast cancer and thus require treatment, reducing the burden of overtreatment in future New research may have found a way we can predict which cases of DCIS could develop into invasive breast cancer and thus require treatment, reducing the burden of overtreatment in future

by Jacob Smith | Analysis | 20 June 2023

20 June 2023

Cachexia is a complex syndrome which has puzzled researchers for decades. But with new research from Cancer Grand Challenges, we could be close to uncovering its mysteries. Cachexia is a complex syndrome which has puzzled researchers for decades. But with new research from Cancer Grand Challenges, we could be close to uncovering its mysteries.

by Sophie Wedekind | In depth | 19 June 2023

19 June 2023

An elderly male patient sat on a hospital bed

Ageing is often the ‘forgotten’ cancer risk factor, overshadowed by preventable risk factors like smoking and obesity. Now, Cancer Grand Challenges are bringing bringing the ‘forgotten’ cancer risk factor into the spotlight.  Ageing is often the ‘forgotten’ cancer risk factor, overshadowed by preventable risk factors like smoking and obesity. Now, Cancer Grand Challenges are bringing bringing the ‘forgotten’ cancer risk factor into the spotlight. 

by Jacob Smith | In depth | 29 May 2023

29 May 2023

Andrea receiving chemotherapy.

Chemotherapy-induced peripheral neuropathy (CIPN) is caused by cancer treatment, but there's no way to treat it. Our work is changing that. Chemotherapy-induced peripheral neuropathy (CIPN) is caused by cancer treatment, but there's no way to treat it. Our work is changing that.

by Tim Gunn | In depth | 22 May 2023

22 May 2023

We spoke to Mariam Jamal-Hanjani and asked her to reflect on a career embedded in large-scale, collaborative and ambitious projects…    We spoke to Mariam Jamal-Hanjani and asked her to reflect on a career embedded in large-scale, collaborative and ambitious projects…   

by Phil Prime | In depth | 10 March 2023

10 March 2023