Cancer Grand Challenges

• Science & Technology

E. coli toxin could be linked to rising rates of bowel cancer in younger adults

A team of our Cancer Grand Challenges researchers have found the first specific clue about what could be behind the rise of bowel cancer in under-50s. A team of our Cancer Grand Challenges researchers have found the first specific clue about what could be behind the rise of bowel cancer in under-50s.

23 April 2025

• Science & Technology
• Charity News

Avoiding, rewiring and turning AI on cancer: the latest Cancer Grand Challenges

Cancer Grand Challenges is offering up to £20m funding to teams that can answer seven of the biggest and most important questions in cancer. Cancer Grand Challenges is offering up to £20m funding to teams that can answer seven of the biggest and most important questions in cancer.

5 March 2025

• Health & Medicine

Bowel cancer rates rising in younger adults around the world

Rising rates of early-onset bowel cancer are a “global phenomenon” and some of the steepest increases are happening in England, according to a major new paper we helped fund. Rising rates of early-onset bowel cancer are a “global phenomenon” and some of the steepest increases are happening in England, according to a major new paper we helped fund.

11 December 2024

• Science & Technology

Can we use AI to help our immune systems fight cancer?

With help from a new Nobel Laureate, Cancer Grand Challenges team MATCHMAKERS are developing AI models that can identify the immune cells best equipped to fight different cancers. That should make it possible to improve immunotherapies and match patients with the treatments best suited to them as individuals. With help from a new Nobel Laureate, Cancer Grand Challenges team MATCHMAKERS are developing AI models that can identify the immune cells best equipped to fight different cancers. That should make it possible to improve immunotherapies and match patients with the treatments best suited to them as individuals.

31 October 2024

• Science & Technology

Cancer metabolism: finding how fast-growing cancers get their energy

Cancer Grand Challenges team Rosetta found how some of the most aggressive and hard-to-treat breast cancers get the energy they need to grow and spread so quickly. Now we can see about slowing them down for good. Cancer Grand Challenges team Rosetta found how some of the most aggressive and hard-to-treat breast cancers get the energy they need to grow and spread so quickly. Now we can see about slowing them down for good.

24 September 2024

• Health & Medicine

Cancer rates rising in under-50s

Early-onset cancer is a growing problem. Cancer rates in 25 to 49-year-olds increased by 24% from 1995 to 2019, according to our latest data. Early-onset cancer is a growing problem. Cancer rates in 25 to 49-year-olds increased by 24% from 1995 to 2019, according to our latest data.

3 June 2024

• Science & Technology

The ‘mystery’ culprit causing kidney cancer worldwide

Researchers from the Cancer Grand Challenges Mutographs team have identified a previously unknown mutational signature in the DNA of kidney cancer across 11 countries Researchers from the Cancer Grand Challenges Mutographs team have identified a previously unknown mutational signature in the DNA of kidney cancer across 11 countries

1 May 2024

• Charity News
• For Supporters

Cancer Research UK partners with The Mark Foundation for Cancer Research to pave way for personalised immunotherapy treatments

The Mark Foundation for Cancer Research has partnered with Cancer Research UK to fund a new Cancer Grand Challenges team. The Mark Foundation for Cancer Research has partnered with Cancer Research UK to fund a new Cancer Grand Challenges team.

7 March 2024

• Charity News
• Health & Medicine
• Science & Technology

Cancer Grand Challenges gives a record £100m to five cancer research teams

Cancer Grand Challenges has awarded five research teams up to £20m each in its largest ever funding round. They will now take on four of the biggest questions in cancer.   Cancer Grand Challenges has awarded five research teams up to £20m each in its largest ever funding round. They will now take on four of the biggest questions in cancer.  

6 March 2024

• Science & Technology

From lemonade stand to grand challenge: changing how we treat cancer in children and young people

Cancer Grand Challenges team KOODAC are changing how we treat cancer in children and young people. Children made their work possible. Cancer Grand Challenges team KOODAC are changing how we treat cancer in children and young people. Children made their work possible.

6 March 2024