Clinical trials

• Personal Stories

Looking back at a life-changing clinical trial

In an unusual turn of events, the results of a clinical trial for mitoxantrone turned out to be so effective that the randomisation of the trial was halted early.  In an unusual turn of events, the results of a clinical trial for mitoxantrone turned out to be so effective that the randomisation of the trial was halted early. 

16 September 2022

• For Researchers

Government update on the Clinical Research Vision: More needed to go beyond recovery?

Is the Government's implementation plan for its 10-year clinical research vision any more than just rhetoric? Our policy team give us the low-down... Is the Government's implementation plan for its 10-year clinical research vision any more than just rhetoric? Our policy team give us the low-down...

30 June 2022

• Health & Medicine

Cannabis, cannabinoids and cancer – the evidence so far

The current consensus is that, right now, there isn’t a large enough body of evidence to prove that cannabis (or any of its active compounds or derivatives) can reliably treat any form of cancer but the medical use of cannabis to treat cancer-related chronic pain is approved in the UK. The current consensus is that, right now, there isn’t a large enough body of evidence to prove that cannabis (or any of its active compounds or derivatives) can reliably treat any form of cancer but the medical use of cannabis to treat cancer-related chronic pain is approved in the UK.

13 May 2022

• Health & Medicine

Triple negative breast cancer drug given initial ‘no’ for NHS in England

Sacituzumab govitecan (Trodelvy) is not being recommended by NICE for use in England as a treatment for some people with triple-negative breast cancer. Sacituzumab govitecan (Trodelvy) is not being recommended by NICE for use in England as a treatment for some people with triple-negative breast cancer.

8 April 2022

• Health & Medicine

Aromatase inhibitors cut breast cancer recurrence in younger patients

A study by Oxford University has found that aromatase inhibitors are better than tamoxifen at reducing the risk of breast cancer recurrence in both younger and older women. A study by Oxford University has found that aromatase inhibitors are better than tamoxifen at reducing the risk of breast cancer recurrence in both younger and older women.

11 February 2022

• Health & Medicine
• Science & Technology

Diving into our role in 50 top cancer drugs

To mark 20 years since the merger of the Cancer Research Campaign and the Imperial Cancer Research Fund, we’ve delved into the research of the charities' that led to many of the drugs in use today. To mark 20 years since the merger of the Cancer Research Campaign and the Imperial Cancer Research Fund, we’ve delved into the research of the charities' that led to many of the drugs in use today.

9 February 2022

• For Researchers

Professor Eithne Costello: On the road to early detection

Professor Eithne Costello on the challenges of ambitious trials, the evolution of early detection as a field in its own right and why a guiding framework is all important. Professor Eithne Costello on the challenges of ambitious trials, the evolution of early detection as a field in its own right and why a guiding framework is all important.

12 November 2021

• For Researchers

Taking on DNA repair to tackle cancer

Pioneering therapeutics targeting the damage repair mechanism of DNA polymerase theta in a range of cancers have entered human trials - we tell the story from discovery to translation. Pioneering therapeutics targeting the damage repair mechanism of DNA polymerase theta in a range of cancers have entered human trials - we tell the story from discovery to translation.

5 November 2021

• For Researchers

Recognising the essential role of clinical research nurses

We hear from Rosie Lomas - the 'Excellence in Cancer Research Nursing Award' winner - and the other shortlisted nurses about their work and the vital role they play in delivering clinical trials. We hear from Rosie Lomas - the 'Excellence in Cancer Research Nursing Award' winner - and the other shortlisted nurses about their work and the vital role they play in delivering clinical trials.

13 October 2021

• Science & Technology
• Health & Medicine

Precision drug slows progression of advanced breast cancer

Patients taking the drug trastuzumab deruxecan were 72% less likely to see their cancer grow significantly or to die than those on an existing breast cancer treatment. Patients taking the drug trastuzumab deruxecan were 72% less likely to see their cancer grow significantly or to die than those on an existing breast cancer treatment.

21 September 2021

• Science & Technology
• Health & Medicine

Cancer Research UK reports record levels of investment in its spinouts

The charity’s commercial arm saw the amount of money from both internal and external sources invested in its spinouts more than double in the last year. The charity’s commercial arm saw the amount of money from both internal and external sources invested in its spinouts more than double in the last year.

24 August 2021