Drug resistance

• Science & Technology
• Health & Medicine

How erectile dysfunction drugs could be the key to overcoming treatment resistance in oesophageal cancer

Researchers have found a drug that targets the tumour microenvironment that could improve treatment for certain cancers. But it might not be the kind of drug you expect.  Researchers have found a drug that targets the tumour microenvironment that could improve treatment for certain cancers. But it might not be the kind of drug you expect. 

21 June 2022

• Science & Technology
• Health & Medicine

Prising open the trap: Getting to grips with targeted cancer drug resistance

Cancer Research UK-funded scientists are using innovative techniques to understand how resistance to a targeted cancer drug is unfolding. Cancer Research UK-funded scientists are using innovative techniques to understand how resistance to a targeted cancer drug is unfolding.

10 January 2022

• Science & Technology

Antibiotic shows potential in helping treat aggressive blood cancer

New research shows a type of aggressive blood cancer could be made more sensitive to chemotherapy using an antibiotic currently available to treat diarrhoea. New research shows a type of aggressive blood cancer could be made more sensitive to chemotherapy using an antibiotic currently available to treat diarrhoea.

24 February 2021

Cancer cells hijack healthy cells to regrow after treatment

Chemotherapy can cause some of the healthy cells surrounding a tumour to make proteins that encourage hardy tumour cells to start growing again Chemotherapy can cause some of the healthy cells surrounding a tumour to make proteins that encourage hardy tumour cells to start growing again

24 November 2016

• Science & Technology
• Health & Medicine

Blood test could predict best treatment for lung cancer

A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment, according to new research published in Nature Medicine. A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment, according to new research published in Nature Medicine.

21 November 2016

Genetic chaos in tumours could help predict chemo response

Cancer Research UK scientists have shown how the level of genetic chaos in tumours could help predict patients’ response to chemotherapy. Cancer Research UK scientists have shown how the level of genetic chaos in tumours could help predict patients’ response to chemotherapy.

4 August 2015

• Health & Medicine

Calming down immune cells could hold key to melanoma treatment

Immune cells may be responsible for drug resistance in melanoma patients, according to research published in Cancer Discovery. Immune cells may be responsible for drug resistance in melanoma patients, according to research published in Cancer Discovery.

25 September 2014

Queen’s University Belfast researchers’ breakthrough leads to new clinical trial in bowel cancer

Scientists have discovered how two genes cause bowel cancer cells to become resistant to treatments used against the disease. Scientists have discovered how two genes cause bowel cancer cells to become resistant to treatments used against the disease.

18 July 2014

Scientists find new way to combat drug resistance in skin cancer

Rapid resistance to vemurafenib - a treatment for a type of skin cancer - could be prevented by blocking a druggable family of proteins Rapid resistance to vemurafenib - a treatment for a type of skin cancer - could be prevented by blocking a druggable family of proteins

22 May 2014

Evolving ovarian cancer cells 'dodge' treatment with chemotherapy

Cancer Research UK scientists have discovered that the commonest type of ovarian cancer evolves at a startling rate, which may allow cancer cells to 'dodge' the current standard treatment, reveals research in The Journal of Pathology today. Cancer Research UK scientists have discovered that the commonest type of ovarian cancer evolves at a startling rate, which may allow cancer cells to 'dodge' the current standard treatment, reveals research in The Journal of Pathology today.

19 December 2011

Scientists discover how to beat resistance to standard leukaemia drug

Cancer Research UK-funded scientists at The Institute of Cancer Research (ICR) have revealed a technique to kill chronic myeloid leukaemia (CML) cells that have stopped responding to a targeted drug, according to research published in Cancer Cell today. Cancer Research UK-funded scientists at The Institute of Cancer Research (ICR) have revealed a technique to kill chronic myeloid leukaemia (CML) cells that have stopped responding to a targeted drug, according to research published in Cancer Cell today.

8 December 2011

New cancer imaging technique uses vitamin C to detect more aggressive tumours

Cancer Research UK scientists have developed a new imaging technique that uses vitamin C to detect cancers likely to be more aggressive or resistant to treatment. Cancer Research UK scientists have developed a new imaging technique that uses vitamin C to detect cancers likely to be more aggressive or resistant to treatment.

3 August 2011