Clinical trials

Professor Eithne Costello on the challenges of ambitious trials, the evolution of early detection as a field in its own right and why a guiding framework is all important.

Pioneering therapeutics targeting the damage repair mechanism of DNA polymerase theta in a range of cancers have entered human trials – we tell the story from discovery to translation.

We hear from Rosie Lomas – the ‘Excellence in Cancer Research Nursing Award’ winner – and the other shortlisted nurses about their work and the vital role they play in delivering clinical trials.

Patients taking the drug trastuzumab deruxecan were 72% less likely to see their cancer grow significantly or to die than those on an existing breast cancer treatment.

Find out how the chemistry inside plants can lead to life-changing drugs and how a cannabis-derived drug is part of a new trial to help people with a type of aggressive brain cancer.

Right now there isn’t enough reliable evidence to prove that any form of cannabis can effectively treat cancer in patients.

The charity’s commercial arm saw the amount of money from both internal and external sources invested in its spinouts more than double in the last year.

Cancer Research UK is collaborating with Aleta Biotherapeutics (Aleta) to trial a new therapy that ‘reboots’ a treatment for some people with blood cancer whose cancer starts to come back.

Cancer Research UK’s spin-out, GammaDelta Therapeutics, has been given approval to trial its unique T-cell therapy in the US.  

One of the biggest meetings of the world’s cancer specialists took place this weekend. Here’s a flavour of the some of the top research presented.