• Science & Technology

Gene editing uncovers potential drug targets for aggressive brain tumours

Potential new drug targets for an aggressive type of brain tumour have been uncovered in the lab, thanks to a ‘reverse engineering’ approach using DNA editing. Potential new drug targets for an aggressive type of brain tumour have been uncovered in the lab, thanks to a ‘reverse engineering’ approach using DNA editing.

18 April 2019

• Science & Technology

Why do certain faulty genes only cause cancer in some parts of the body?

Our international team of scientists are tackling a fundamental question about how cancer develops: why do some gene faults only cause cancer in certain organs? Our international team of scientists are tackling a fundamental question about how cancer develops: why do some gene faults only cause cancer in certain organs?

10 April 2019

• Science & Technology

Scientists use DNA-editing tool CRISPR to catalogue cancer’s weaknesses

UK scientists are putting together a list of the most promising potential cancer drug targets in one of the largest lab studies of its kind. UK scientists are putting together a list of the most promising potential cancer drug targets in one of the largest lab studies of its kind.

10 April 2019

• Health & Medicine

Immune-stimulating injection turns tumours into ‘cancer vaccine factories’ in mice

Injecting immune cell stimulants directly into a tumour could help the immune system spot and attack cancer cells, according to new research in mice. Injecting immune cell stimulants directly into a tumour could help the immune system spot and attack cancer cells, according to new research in mice.

8 April 2019

• Science & Technology

Inflammation and cancer: unravelling a 150-year-old mystery

Inflammation can prevent infections and helps repair injuries. But for people with long-term inflammatory conditions, it can sometimes lead to cancer. Inflammation can prevent infections and helps repair injuries. But for people with long-term inflammatory conditions, it can sometimes lead to cancer.

28 March 2019

• Science & Technology
• Health & Medicine

Could the bacteria in our gut help treat cancer?

Gut bacteria may help some bowel cancers grow. Our Grand Challenge scientists want to see if tinkering with these tiny communities could be a new way to treat cancer. Gut bacteria may help some bowel cancers grow. Our Grand Challenge scientists want to see if tinkering with these tiny communities could be a new way to treat cancer.

21 March 2019

• Science & Technology

The immune system preys on growing lung cancers, forcing them to evolve to survive

Scientists are taking a leaf out of Darwin's evolutionary handbook to understand how lung cancer evolves. Scientists are taking a leaf out of Darwin's evolutionary handbook to understand how lung cancer evolves.

20 March 2019

• Science & Technology

Cell culture shock – a scientist’s hunt for the perfect cocktail

Lab-grown cells live on liquid food called cell culture media. But off-the-shelf recipes could be skewing experiments, posing a challenge for cancer research. Lab-grown cells live on liquid food called cell culture media. But off-the-shelf recipes could be skewing experiments, posing a challenge for cancer research.

18 March 2019

• Science & Technology
• Health & Medicine

Rewriting the breast cancer rulebook 

Our scientists have found that breast cancer is not 1 but 10 different diseases, each with a different risk of coming back or spreading. Our scientists have found that breast cancer is not 1 but 10 different diseases, each with a different risk of coming back or spreading.

13 March 2019

• Health & Medicine

Molecular patterns could better predict breast cancer recurrence

New research suggests the genetic and molecular make-up of individual breast tumours holds clues to how a woman’s disease could progress. New research suggests the genetic and molecular make-up of individual breast tumours holds clues to how a woman’s disease could progress.

13 March 2019

• Science & Technology

Study in mice suggests why cancer commonly spreads to the liver

Researchers have pinpointed cells in the livers of mice that create an environment cancer cells might need to settle and grow there. Researchers have pinpointed cells in the livers of mice that create an environment cancer cells might need to settle and grow there.

7 March 2019