Skip to main content

Together we are beating cancer

Donate now
  • Health & Medicine

Prostate cancer drug given initial ‘no’ for NHS in England

The Cancer Research UK logo
by Cancer Research UK | News

7 June 2018

0 comments 0 comments

Photo of man with lots of files

A prostate cancer drug has been provisionally rejected as a first-line treatment on the NHS in England.

The draft recommendation from the National Institute for Health and Care Excellence (NICE) means abiraterone (Zytiga) won’t be made routinely available for men with newly diagnosed prostate cancer that has spread to other parts of the body.

As it stands, the NHS in England can only prescribe abiraterone for these men once standard hormone treatment or chemotherapy has failed.

Results from recent clinical trials have shown that giving abiraterone alongside steroids and hormone therapy as a first-line treatment can reduce the chance of the cancer coming back and improve survival compared to hormone therapy alone.

Sir Harpal Kumar, Cancer Research UK’s chief executive, called the decision “disappointing”. “Two clinical trials published last year provided compelling evidence of the huge potential benefit of abiraterone for these patients,” he said.

What does the decision mean?

NICE published its draft recommendation this week, rejecting abiraterone as a first-line therapy. The committee concluded they couldn’t accurately estimate the drug’s cost effectiveness based on the data submitted.

The drug’s manufacturer, Janssen, can now submit additional data, which will be reviewed later this summer before a final decision is reached.

A NICE spokesperson told The Telegraph: “We understand that some men with prostate cancer will be disappointed by today’s news.

“However, we can only recommend drugs that are clinically effective and show value for money compared to current treatment options. In this case, abiraterone has fallen short.”

Kumar urged NICE and Janssen to work together quickly to provide the information that will allow the drug to be recommended.