Skip to main content

Together we are beating cancer

Donate now
  • Policy & Insight

Research clusters: How the Industrial Strategy can enhance the UK life sciences ecosystems

by Emma Cattermole , Amal Iman | Analysis

12 March 2025

0 comments 0 comments

A shot of our Cambridge Institute at night

The success of the research we fund for people affected by cancer is dependent on a thriving UK research and development (R&D) ecosystem that can attract investment, world-leading researchers and has the tools and facilities needed to do excellent research.  

Research clusters bring together densities of talented people, institutions, infrastructure, technology, investment and networks to work on specific themes, which boosts and accelerates R&D. We’ve helped develop some of the UK’s leading life sciences clusters, allowing us to carry out our research as well as deliver on the UK’s Government’s priorities. 

Now we’re sharing our expertise on this in our new report, Clusters: Investing for impact, to help demonstrate their potential in boosting the UK’s research environment and provide a framework for governments to deliver targeted support. 

With the upcoming development and delivery of the industrial strategy, life science sector plan, the 10 Year Health Plan, alongside further devolved and local growth plans, there are huge opportunities for governments to strengthen the UK R&D landscape.  

That’s why we’re urging the government to:  

  • Take calculated risks and support leaders who have a visionary approach to the development of thriving clusters  
  • Work with partners who understand what their sectors and local areas need to constantly curate clusters over the long term  
  • Use the criteria for clusters set out in our report as a framework to create the globally leading environments of the future   

Read our report

Research clusters drive impact

Through co-location and connection, the components of a cluster become more than the sum of their parts, promoting collaboration and knowledge spillovers, resulting in more and better research outputs and innovation, as well as access to finance and commercialisation opportunities.  

An infographic illustrating how research clusters can help to create a positive feedback loop to drive impact

The need for a strategic approach to research investment

The UK has long been at the forefront of life sciences research on the international stage. It’s home to leading scientific institutions, like the Francis Crick Institute, has a history of attracting world-class scientists and hosts a leading university sector. But with an increasingly competitive global research environment, and the UK’s position on this stage beginning to wobble, it’s becoming increasingly important for the government to invest in the UK’s R&D ecosystem and secure its position.   

In a constrained fiscal environment, it’s essential the UK makes the most of every penny spent on research. Investing in strengthening research clusters is a means to do that. As we set out here, clusters strengthen UK research as a whole and boost the economy. They can help kick start progress towards both the UK Governments health and growth missions and our vision of beating cancer sooner.  

To drive more of this success, governments at a UK, devolved and local level must be strategic and visionary.  

How governments can learn from us

Because it’s so central to our mission to beat cancer sooner, we have made long-term, strategic investment into the cancer research ecosystem in the UK. We’ve taken this strategic approach because every pound we spend on research has come from the generosity of our supporters, so we have a responsibility to use their money in the most impactful way possible. 

Of the £4 billion that we’ve invested in research over the last decade, we’ve made diverse investments to bolster research infrastructure and capabilities in the UK.  

This has helped develop some of the world’s leading life sciences clusters in the UK and fostered an environment where research can thrive.  

This is boosting UK cancer research, enhancing collaborations and bringing together fields and stages of the research pipeline to accelerate innovative developments to beat cancer sooner.

From our experience, we have developed our five ‘Criteria for Clusters’. The case studies in our report demonstrate our success in places where we have made strategic, long-term investments and the impact this has on our research and those research ecosystems. 

The Five Criteria for Clusters

This framework can be used by the UK, devolved and local governments to assess the potential of a place to be a world-leading cluster, identify its unique strengths and develop targeted actions to fill gaps.  

The five keys to cluster success:  

  1. Political will with a strategic and visionary approach  
  2. Proximity of diverse research-performing organisations at all stages of the research pipeline  
  3. Opportunities to create connection and collaboration to spark innovation and accelerate research pipelines 
  4. Access to finance, research infrastructure and talent  
  5. Attractive local environment  

Life sciences in London 

Having now become Europe’s largest biomedical institute, the Francis Crick Institute and the surrounding Knowledge Quarter in London is an example of the success of a visionary approach. 

Combining strong foundations for research and innovation, transport links, government support, diverse investment and major partnerships, King’s Cross in London is becoming a world-leading environment for life sciences and AI. 

The presence of the Crick – a major partnership between us, Wellcome, universities and government – has helped the positive feedback cycle that has transformed this area. By providing a world-leading hub for research and collaboration, the institute is helping attract a concentration of expertise and critical mass of researchers. This has drawn in major global industry – in life sciences and other knowledge-based sectors – like Google, McKinsey and GSK. 

There is an opportunity to apply this visionary approach to more places in the UK with the potential to be world-leading clusters. Achieving this requires sustained political will, strategic investment and coordination between local and national government, research leaders and investors. 

As the second largest independent research funder in the UK, we invest to have the greatest impact for people affected by cancer.

Our funding helps the strategic development of world-leading centres of research excellence here in the UK. Our bench-to-business-to-bedside approach also ensures we attract researchers and inward investment from across the world into our new start-up biotech and medtech ventures which employ thousands of people in highly skilled jobs.

The case studies in this report show how our investment in clusters drive this impact, and how UK, devolved and local governments can boost the UK R&D ecosystem by supporting the further development of UK research clusters.

- Iain Foulkes, executive director of research and innovation at Cancer Research UK

Cancer Research UK’s investments in Cambridge and Manchester 

The presence and proximity of world-leading cancer research and care in Manchester and Cambridge provides the opportunity to connect and accelerate the full life cycle of research, with patients at the forefront, and drive impact. 

Our long-term, diverse investments in these cities have helped cultivate environments where cancer research can thrive, and be connected with the wider multidisciplinary ecosystem to maximise collaboration and spillover. 

The presence of our institute and centre in Cambridge enables our research to benefit from a multidisciplinary research ecosystem, with collaborations across the university, hospitals and industry. Our institute sits around a roundabout with the MRC Laboratory of Molecular Biology, and new AstraZeneca Discovery Research Centre, just up the road from Addenbrooke’s Hospital. We hosted AstraZeneca researchers while they developed their site, leading to the development of 10 drugs currently in trials, and ongoing collaborations now we are neighbours. 

Our example from Manchester, of a collective effort to develop a biomarker for responsiveness to immunotherapy, benefited from the proximity of Cancer Research UK infrastructure including our biomarker centre and biobank, the Christie Hospital and local community programmes, shows how these connections can fast-track research. It is also shows how networks between clusters can further benefit research – where our network between researchers in Manchester and London have helped identify additional clinical uses for the biomarker.   

In our report, we highlight some of the specific challenges of further development of each of these places and how our criteria can untangle these to enable governments to deliver targeted support to take clusters to new levels.  

Cancer Research UK Scotland Institute   

We know the strengths that clusters bring to R&D and that’s why we’re working on a new partnership, led by the Universities of Edinburgh and Glasgow, to develop a new world-leading biomedical research institute and cluster. This will be centred in Scotland and bridge out to the North-East of England, acting as a magnet for talent, investment and industry collaborations from around the world, into the broader Scottish life sciences environment.  

Taking UK life sciences to a new level 

We’ve published this report today to demonstrate the impact of research clusters and highlight the potential for maximising research and innovation in the UK.  

We know that the government sees the value of clusters in meeting its growth ambitions, with their recent commitment to the Oxford-Cambridge Growth Corridor an important step on the road to achieving this.  

This report will support governments to make the most of upcoming opportunities to create a thriving life sciences system in an increasingly globally competitive environment and most importantly to help us achieve our mission of beating cancer sooner.   

Tell us what you think

Leave a Reply

Your email address will not be published. Required fields are marked *

Read our comment policy.

Tell us what you think

Leave a Reply

Your email address will not be published. Required fields are marked *

Read our comment policy.