Drug discovery and development

• Science & Technology

From lemonade stand to grand challenge: changing how we treat cancer in children and young people

Cancer Grand Challenges team KOODAC are changing how we treat cancer in children and young people. Children made their work possible. Cancer Grand Challenges team KOODAC are changing how we treat cancer in children and young people. Children made their work possible.

6 March 2024

• For Researchers

MOv18 - opening a new front for immunotherapy

Follow Sophia Karagiannis and James Spicer on an immunological adventure as they develop a ground-breaking new class of drug... Follow Sophia Karagiannis and James Spicer on an immunological adventure as they develop a ground-breaking new class of drug...

12 December 2023

• Science & Technology

How MRI add-ons could accelerate the development of new treatments

New research from the ICR is showing us how additional measurements taken by MRI could speed up the development of new drugs that could make chemotherapies more effective New research from the ICR is showing us how additional measurements taken by MRI could speed up the development of new drugs that could make chemotherapies more effective

9 May 2023

• Health & Medicine

FOCUS4: Learning from a landmark clinical trial

FOCUS4 was a large-scale trial investigating new treatments in people with advanced or metastatic colorectal cancer. Running it may not have been without its challenges, but the learnings it provided us with are invaluable if we're to run trials like it again.  FOCUS4 was a large-scale trial investigating new treatments in people with advanced or metastatic colorectal cancer. Running it may not have been without its challenges, but the learnings it provided us with are invaluable if we're to run trials like it again. 

25 April 2023

• For Researchers

The power of partnership – the unique alliance taking on brain cancer

The Antibody Alliance Laboratory – a collaboration between Cancer Research UK and AstraZeneca – combines academic rigour with agile bioengineering to push forward antibody discovery projects... The Antibody Alliance Laboratory – a collaboration between Cancer Research UK and AstraZeneca – combines academic rigour with agile bioengineering to push forward antibody discovery projects...

15 December 2022

• Science & Technology
• Health & Medicine

Repurposing radiotherapy drugs could give immunotherapy a boost

Researchers in Southampton have found a way to improve the effectiveness of immunotherapy in cancers that are resistant by repurposing existing drugs Researchers in Southampton have found a way to improve the effectiveness of immunotherapy in cancers that are resistant by repurposing existing drugs

11 November 2022

• Personal Stories

Looking back at a life-changing clinical trial

In an unusual turn of events, the results of a clinical trial for mitoxantrone turned out to be so effective that the randomisation of the trial was halted early.  In an unusual turn of events, the results of a clinical trial for mitoxantrone turned out to be so effective that the randomisation of the trial was halted early. 

16 September 2022

• Science & Technology

How we are working with industry to translate research into real benefits for patients 

You may not know that as well as funding cancer research, we also work with industry and academia to develop promising ideas and turn them into real benefit for patients. Find out about Cancer Research Horizons. You may not know that as well as funding cancer research, we also work with industry and academia to develop promising ideas and turn them into real benefit for patients. Find out about Cancer Research Horizons.

26 April 2022

• For Researchers

A new approach to cancer immunotherapy

Forty years ago, hints of a new component of the immune system caused a stir. Here, we chart the story of gamma delta T cells from discovery to clinical trials... Forty years ago, hints of a new component of the immune system caused a stir. Here, we chart the story of gamma delta T cells from discovery to clinical trials...

18 March 2022

• Science & Technology

Paving the way: How biopsies are offering hope to children with aggressive brain tumours

7 March 2022

• Science & Technology
• Health & Medicine

Diving into our role in 50 top cancer drugs

To mark 20 years since the merger of the Cancer Research Campaign and the Imperial Cancer Research Fund, we’ve delved into the research of the charities' that led to many of the drugs in use today. To mark 20 years since the merger of the Cancer Research Campaign and the Imperial Cancer Research Fund, we’ve delved into the research of the charities' that led to many of the drugs in use today.

9 February 2022

• For Researchers

Taking on DNA repair to tackle cancer

Pioneering therapeutics targeting the damage repair mechanism of DNA polymerase theta in a range of cancers have entered human trials - we tell the story from discovery to translation. Pioneering therapeutics targeting the damage repair mechanism of DNA polymerase theta in a range of cancers have entered human trials - we tell the story from discovery to translation.

5 November 2021