Cancer biology

• Health & Medicine
• Personal Stories

Li Fraumeni Syndrome and the start of precision cancer prevention

We're funding the UK's first precision cancer prevention trial unit. It's testing a drug that could help protect people with Li Fraumeni Syndrome, a genetic condition that can lead to a more than 90% lifetime risk of cancer, against the disease. We're funding the UK's first precision cancer prevention trial unit. It's testing a drug that could help protect people with Li Fraumeni Syndrome, a genetic condition that can lead to a more than 90% lifetime risk of cancer, against the disease.

19 September 2023

• Science & Technology
• Health & Medicine

Sugar and cancer – what you need to know

We take a look at claims that sugar 'feeds' cancer cells and explore the links between the amount of sugar in our diets and obesity. We take a look at claims that sugar 'feeds' cancer cells and explore the links between the amount of sugar in our diets and obesity.

16 August 2023

• Science & Technology

What can elephants teach us about cancer?

For World Elephant Day, we're taking a look at why elephants so rarely get cancer. Could the ways they protect themselves help people too? For World Elephant Day, we're taking a look at why elephants so rarely get cancer. Could the ways they protect themselves help people too?

12 August 2023

• For Researchers

Moving target – retrotransposable elements and cancer

Links between retrotransposable elements and cancer have deep roots – George Kassiotis gets into their chequered past and how we might utilise these ancient viral infections   Links between retrotransposable elements and cancer have deep roots – George Kassiotis gets into their chequered past and how we might utilise these ancient viral infections  

11 July 2023

• For Researchers

A new culture – how CRUK is helping to take organoids global

Cancer patient-derived organoids from Japan’s Fukushima Medical University have become the latest technology to be made available via CancerTools.org Cancer patient-derived organoids from Japan’s Fukushima Medical University have become the latest technology to be made available via CancerTools.org

19 June 2023

• Health & Medicine

FOCUS4: Learning from a landmark clinical trial

FOCUS4 was a large-scale trial investigating new treatments in people with advanced or metastatic colorectal cancer. Running it may not have been without its challenges, but the learnings it provided us with are invaluable if we're to run trials like it again.  FOCUS4 was a large-scale trial investigating new treatments in people with advanced or metastatic colorectal cancer. Running it may not have been without its challenges, but the learnings it provided us with are invaluable if we're to run trials like it again. 

25 April 2023

• For Researchers

A career forged in team science

We spoke to Mariam Jamal-Hanjani and asked her to reflect on a career embedded in large-scale, collaborative and ambitious projects…    We spoke to Mariam Jamal-Hanjani and asked her to reflect on a career embedded in large-scale, collaborative and ambitious projects…   

10 March 2023

• Science & Technology
• Health & Medicine

Time to take on 9 new Cancer Grand Challenges

These are some of the biggest questions in cancer research. Cancer Grand Challenges are looking for research teams that can help answer them. These are some of the biggest questions in cancer research. Cancer Grand Challenges are looking for research teams that can help answer them.

8 March 2023

• Science & Technology

Can cancer cells communicate?

Cancer cells use electricity to help them spread. A new study shows it might be key to controlling their other behaviours, too. Cancer cells use electricity to help them spread. A new study shows it might be key to controlling their other behaviours, too.

28 February 2023

• Science & Technology

The ecDNA story – catching the mastermind behind cancer evolution

Aggressive cancers use ecDNA to evolve quickly and resist treatment. This is how we found that out, and how we're going to stop it. Aggressive cancers use ecDNA to evolve quickly and resist treatment. This is how we found that out, and how we're going to stop it.

20 February 2023

• For Researchers

Hacking cancer cell metabolism

Restricting cancer cells of specific amino acids can slow tumour growth and sharpen the effects of chemotherapy and radiotherapy – now, startup Faeth Therapeutics is creating precision diets which can enhance cancer treatments. Restricting cancer cells of specific amino acids can slow tumour growth and sharpen the effects of chemotherapy and radiotherapy – now, startup Faeth Therapeutics is creating precision diets which can enhance cancer treatments.

30 January 2023

• For Researchers

The power of partnership – the unique alliance taking on brain cancer

The Antibody Alliance Laboratory – a collaboration between Cancer Research UK and AstraZeneca – combines academic rigour with agile bioengineering to push forward antibody discovery projects... The Antibody Alliance Laboratory – a collaboration between Cancer Research UK and AstraZeneca – combines academic rigour with agile bioengineering to push forward antibody discovery projects...

15 December 2022