• For Researchers

Taking on DNA repair to tackle cancer

Pioneering therapeutics targeting the damage repair mechanism of DNA polymerase theta in a range of cancers have entered human trials - we tell the story from discovery to translation. Pioneering therapeutics targeting the damage repair mechanism of DNA polymerase theta in a range of cancers have entered human trials - we tell the story from discovery to translation.

5 November 2021

• Science & Technology

Unravelling the mystery of Barrett’s oesophagus

Barrett’s oesophagus affects around 1 in every 100 to 200 people in the UK, and, for a small number of people, can develop into oesophageal cancer. But the origins of the condition have remained a mystery for decades, until now. Barrett’s oesophagus affects around 1 in every 100 to 200 people in the UK, and, for a small number of people, can develop into oesophageal cancer. But the origins of the condition have remained a mystery for decades, until now.

25 October 2021

• For Researchers
• Science & Technology

How cancer hijacks cell death: a new view of metastasis

Professor Jody Rosenblatt tells us why dysregulated cell death could have an impact not only on metastasis, but also therapy resistance. Professor Jody Rosenblatt tells us why dysregulated cell death could have an impact not only on metastasis, but also therapy resistance.

17 September 2021

• Science & Technology

Scientists find cells in centre of tumours are most likely to spread

The new findings shed light on how cancer cells found in different parts of a tumour behave differently. The new findings shed light on how cancer cells found in different parts of a tumour behave differently.

19 May 2021

• Science & Technology

Stressed out – the cancer cells that survive chemotherapy, but at a cost

A group of Cancer Research UK-funded scientists are beginning to discover new vulnerabilities in cancer cells, which emerge when they enter ‘survival mode’. A group of Cancer Research UK-funded scientists are beginning to discover new vulnerabilities in cancer cells, which emerge when they enter ‘survival mode’.

29 April 2021

• Science & Technology

New method analyses DNA changes with ‘unprecedented accuracy’

Using the technology, scientists have revealed that cell division isn’t necessarily the main cause of genetic changes in human tissue DNA. Using the technology, scientists have revealed that cell division isn’t necessarily the main cause of genetic changes in human tissue DNA.

29 April 2021

• Science & Technology

Mutations in overlooked DNA could have profound impact on bowel cancer survival

DNA errors in the cell’s energy ‘factories’ increases the chances of survival for people with bowel cancer, according to a new study. DNA errors in the cell’s energy ‘factories’ increases the chances of survival for people with bowel cancer, according to a new study.

8 April 2021

• Science & Technology

Changes detected in BRCA1 breast cells before they turn cancerous

Scientists have mapped out some of the earliest changes that occur in seemingly healthy breast tissue long before any tumours appear. Scientists have mapped out some of the earliest changes that occur in seemingly healthy breast tissue long before any tumours appear.

8 March 2021

• Science & Technology

Antibiotic shows potential in helping treat aggressive blood cancer

New research shows a type of aggressive blood cancer could be made more sensitive to chemotherapy using an antibiotic currently available to treat diarrhoea. New research shows a type of aggressive blood cancer could be made more sensitive to chemotherapy using an antibiotic currently available to treat diarrhoea.

24 February 2021

• Science & Technology

Gentle regular exercise could reduce the risk of liver cancer in mice

A team of Cancer Research UK-funded scientists have been investigating the role of exercise in reducing the risk of liver cancer in mice A team of Cancer Research UK-funded scientists have been investigating the role of exercise in reducing the risk of liver cancer in mice

15 February 2021

• Science & Technology
• Policy & Insight

What could DeepMind ‘solving’ the protein folding problem mean for cancer research?

We asked two of our protein specialists, who are trying to understand how the way proteins fold affect cancer outcomes, to give their verdict on the news. We asked two of our protein specialists, who are trying to understand how the way proteins fold affect cancer outcomes, to give their verdict on the news.

23 December 2020

• Science & Technology

The long road to targeting the holy grail of the immune response

A team of our scientists at University College London have developed a potential new immunotherapy drug and caused another paradigm shift in our understanding of how cancer immunotherapy works. A team of our scientists at University College London have developed a potential new immunotherapy drug and caused another paradigm shift in our understanding of how cancer immunotherapy works.

9 November 2020