• For Researchers

Thinking outside the chromosome – how ecDNA is challenging conventional thinking

What is extrachromosomal DNA? How have we come to think of its role in cancer? And what has all this got to do with a flagship lung cancer study? What is extrachromosomal DNA? How have we come to think of its role in cancer? And what has all this got to do with a flagship lung cancer study?

11 November 2022

• Science & Technology
• Health & Medicine

Repurposing radiotherapy drugs could give immunotherapy a boost

Researchers in Southampton have found a way to improve the effectiveness of immunotherapy in cancers that are resistant by repurposing existing drugs Researchers in Southampton have found a way to improve the effectiveness of immunotherapy in cancers that are resistant by repurposing existing drugs

11 November 2022

• Science & Technology

TRACERx EVO, a new programme to transform lung cancer research

Today, we've announced TRACERx EVO, a new programme that builds on the discoveries made in the world’s largest long-term lung study, TRACERx.  Today, we've announced TRACERx EVO, a new programme that builds on the discoveries made in the world’s largest long-term lung study, TRACERx. 

9 November 2022

• Science & Technology

The Nobel Prize winner helping us treat children's cancers

Professor Carolyn Bertozzi won the 2022 Nobel Prize in Chemistry. She's using all she's learned to create better treatments for solid tumours in children. Professor Carolyn Bertozzi won the 2022 Nobel Prize in Chemistry. She's using all she's learned to create better treatments for solid tumours in children.

8 November 2022

• Science & Technology
• Health & Medicine

Changes to chromosomes impact how children's brain tumours respond to treatment

Our scientists have found tiny cellular changes that make medulloblastomas resistant to treatment. Understanding them could help us treat the disease in future. Our scientists have found tiny cellular changes that make medulloblastomas resistant to treatment. Understanding them could help us treat the disease in future.

4 November 2022

• Health & Medicine

6 highlights from our Black in Cancer conference

Many cancers affect Black people differently. Often, their outcomes are worse. There's a long way to go to change that, but this is how we can start. Many cancers affect Black people differently. Often, their outcomes are worse. There's a long way to go to change that, but this is how we can start.

31 October 2022

• Science & Technology

Stopping the spread: A revolution in how we think about metastasis

Research from our Cambridge Institute has shown us that metastasis isn’t a process unique to cancer, revolutionising the way we think about cell dissemination.  Research from our Cambridge Institute has shown us that metastasis isn’t a process unique to cancer, revolutionising the way we think about cell dissemination. 

18 October 2022

• Science & Technology

How “the most advanced machine learning approach” is finding new cancer-causing mutational signatures

A team of researchers has developed a new tool to identify mutational signatures in cancer DNA that's quickly establishing itself as the best of the best.   A team of researchers has developed a new tool to identify mutational signatures in cancer DNA that's quickly establishing itself as the best of the best.  

12 October 2022

• Health & Medicine

Life beyond cancer: Improving the long term side effects for children and young people with brain cancer

We spoke to Dr Debbie Hicks about what is being done to understand and minimise the impact of long-term side effects for children and young people with medulloblastoma. We spoke to Dr Debbie Hicks about what is being done to understand and minimise the impact of long-term side effects for children and young people with medulloblastoma.

22 September 2022

• Science & Technology

Scientists reveal how air pollution can cause lung cancer in people who have never smoked

A long-term study funded by Cancer Research UK has revealed how air pollution can cause lung cancer in people who have never smoked.  A long-term study funded by Cancer Research UK has revealed how air pollution can cause lung cancer in people who have never smoked. 

10 September 2022