Cancer genes

• Science & Technology

So-called 'junk DNA' affects inherited cancer risk

Research reveals how genetic variations in the regions of DNA that don't code for proteins, once dismissed as 'junk DNA', can affect a person's risk of cancer. Research reveals how genetic variations in the regions of DNA that don't code for proteins, once dismissed as 'junk DNA', can affect a person's risk of cancer.

6 December 2019

• Science & Technology

Gene editing uncovers potential drug targets for aggressive brain tumours

Potential new drug targets for an aggressive type of brain tumour have been uncovered in the lab, thanks to a ‘reverse engineering’ approach using DNA editing. Potential new drug targets for an aggressive type of brain tumour have been uncovered in the lab, thanks to a ‘reverse engineering’ approach using DNA editing.

18 April 2019

• Science & Technology

Why do certain faulty genes only cause cancer in some parts of the body?

Our international team of scientists are tackling a fundamental question about how cancer develops: why do some gene faults only cause cancer in certain organs? Our international team of scientists are tackling a fundamental question about how cancer develops: why do some gene faults only cause cancer in certain organs?

10 April 2019

• Science & Technology

Scientists use DNA-editing tool CRISPR to catalogue cancer’s weaknesses

UK scientists are putting together a list of the most promising potential cancer drug targets in one of the largest lab studies of its kind. UK scientists are putting together a list of the most promising potential cancer drug targets in one of the largest lab studies of its kind.

10 April 2019

• Science & Technology

The immune system preys on growing lung cancers, forcing them to evolve to survive

Scientists are taking a leaf out of Darwin's evolutionary handbook to understand how lung cancer evolves. Scientists are taking a leaf out of Darwin's evolutionary handbook to understand how lung cancer evolves.

20 March 2019

• Science & Technology
• Health & Medicine

Rewriting the breast cancer rulebook 

Our scientists have found that breast cancer is not 1 but 10 different diseases, each with a different risk of coming back or spreading. Our scientists have found that breast cancer is not 1 but 10 different diseases, each with a different risk of coming back or spreading.

13 March 2019

• Science & Technology

Downloading the genetic rules of cancer 

Scientists are working to document all the faults in the DNA of cancer cells to help them understand how cancer works. Scientists are working to document all the faults in the DNA of cancer cells to help them understand how cancer works.

4 February 2019

• Science & Technology

Meet the scientists taking on 3 of the biggest challenges in cancer research

Three new teams funded through our Grand Challenge are about to embark on research projects focusing on the microbiome, faulty genes and chronic inflammation. Three new teams funded through our Grand Challenge are about to embark on research projects focusing on the microbiome, faulty genes and chronic inflammation.

23 January 2019

• Science & Technology

Tackling ‘undruggable’ genes in lung and pancreatic cancers is this researcher’s life

Two important cancer genes cooperate to make lung cancers more aggressive in mice, according to new research. Two important cancer genes cooperate to make lung cancers more aggressive in mice, according to new research.

30 November 2017